Immune thrombocytopenia (ITP)

Immune Thrombocytopenia, previously known as Idiopathic or Immune Thrombocytopenic Purpura is a nosographic entity characterised mainly by two elements: isolated thrombocytopenia, meaning there are no alterations in other haematological parameters, and absence of clinical manifestations and symptoms which cannot be directly linked to thrombocytopenia. Bleeding symptoms, when present, generally correlate with severity of the thrombocytopenia. […]

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Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia (CLL) was for many years considered an indolent disease caused by the accumulation of small lymphocytes with disturbed apoptosis. Today the comprehension of the pathogenesis has modified this historical view and allowed the condition to be recognized as a dynamic disease, which originates from a wide range of primary and secondary biological […]

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Acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is a heterogeneous disease with different clinical and biological aspects, characterized by the proliferation and accumulation of immature cells of the lymphoid lineage in the bone marrow, peripheral blood, lymphoid tissues and other tissues.     EPIDEMIOLOGY ALL is the most common tumor in children, while it is relatively rare in […]

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