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Acute promyelocytic leukemia in adult patients

Epidemiology and diagnosis Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML) with peculiar morphologic, cytogenetic, and biomolecular characteristics (1). Most patients are young, present with leukopenia, and exhibit a life-threatening coagulopathy, which is the most relevant manifestation of the disease at diagnosis (2). The disease is relatively rare in adults, […]

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