Tag Archives: APL

Acute myeloid leukemia

AML is a clonal proliferation of hematopoietic stem cells characterized by blocked or severely impaired differentiation of the hematopoietic stem cell, resulting in an accumulation of cells at various stages of incomplete maturation with an associated reduced production of normal hematopoietic elements. As a consequence, various levels of cytopenia usually occur and the clinical manifestations […]

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